Lecture and Exercise Protein Prediction II for Computer Scientists WS18/19

 

Type:

Lecture (4 SWS) + Exercise (2 SWS)

Ects:

8.0

Lecturer

Burkhard Rost  (lecture)

Jonas Reeb (exercise)

Rotation:

Tuesday, 10:00 - 12:00
Thursday, 10:00 - 12:00
Thursday, (exercise), 12:00 - 14:00

Place:

Lecture:  LMU Hörsaal im Physik Werkstattgebäude, Am Coulombwall 1, ground floor, close to Mensa, Garching campus

Exercise: LMU Hörsaal im Physik Werkstattgebäude, Am Coulombwall 1, ground floor, close to Mensa, Garching campus

Exam:

Language:

English

Announcements:

!!!!!THE LECTURE STARTS ON TUESDAY, OCTOBER 23!!!!!

The latest news are always on top!

Exam tba

Content

This lecture continues the 'Protein Prediction I' lecture. The attendance of this lecture however is not a mandatory requirement for 'Protein Prediction II'. Topics will include (but not be limited to):

  • Predicting protein function using sequence: sequence alignments, multiple sequence alignments, motifs, domain assignment, annotation transfer by homology, ab initio predictions.
  • Predicting protein function using structure: structural alignments, structural motifs, annotation transfer via structure similarity.
  • From structure prediction to function prediction: comparative modeling; prediction of: secondary structure, hydrophilicity profiles, solvent accessibility, transmembrane segments, disordered regions, contact maps, functional residues; template free modeling.
  • Machine learning.

Materials

 


 

 

Exercise

  • Watch this space for updates on the tasks

 

 

 

Lecture slides