Lecture and Exercise Protein Prediction II for Bioinformaticians WS16/17

Type:	Lecture (4 SWS) + Exercise (2 SWS)
Ects:	8.0
Lecturer	Burkhard Rost (lecture) tba. (exercise) tba. (exercise)
Rotation:	Tuesday, 12:00 - 13:30 (lecture) Thursday, 12:30 - 14:00 (lecture) (new) Thursday, 11:30 - 12:30 (exercise) (new)
Place:	Lecture: MI 01.09.034 Exercise: MI 01.09.034 Exam: Tuesday, February 7, 18:00 - 19:30, room 01.09.034 Time: 06:00 - 07:30pm Exam review upon request
Language:	English
Announcements:	The latest news are always on top! NO LECTURES ON TUE, NOV. 22 AND THUR, NOV. 24!!!!!!!!!! !!!! THE FIRST LECTURE TAKES PLACE ON TUESDAY, OCT 25!!!!!!! Examen: Feb. 7th (Important: Don't forget to register at TUMonline for the exam) Makeup: March 27th

Content

This lecture continues the 'Protein Prediction' lecture. The attendance of this lecture is however not a mandatory requrement for 'Protein Prediction II'.Topics will include (but not be limited to):

Predicting protein function using sequence: sequence alignments, multiple sequence alignments, motifs, domain assignment, annotation transfer by homology, ab initio predictions.
Predicting protein function using structure: structural alignments, structural motifs, annotation transfer via structure similarity.
From structure prediction to function prediction: comparative modeling; prediction of: secondary structure, hydrophilicity profiles, solvent accessibility, transmembrane segments, disordered regions, contact maps, functional residues; template free modeling.
Machine learning.