Services

Complete Sequence Analysis

PredictProtein

Service for sequence analysis and Protein structure Prediction

 

See the official Rostlab GitHub page for the latest updates and tools. Some tools listed below may be deprecated or discontinued.

 

Structure

Aquaria Identify relevant exerimental 3D structures and generate insight from structures and annotations

AGAPE

Fold recognition without folds: Improved and generalized method for sequence-profile and profile-profile comparisons using sequence and predicted 1D structure

CHOP

CHOPping proteins into structural domain-like fragments

ConSequenceS

Consensus Sequence Searches with PSI-BLAST

DSSPcont

Continuous assignment of Protein Secondary Structure

Meta Disorder (MD)

Protein disorder prediction based on orthogonal sources of information

NORSp

Prediction of NOn-Regular Secondary Structure (NORS)

PROFbval

Prediction of protein flexibility and rigidity prediction from sequence

PROFcon

Prediction of inter-residue contacts

ProfTMB

Prediction of TransMembrane Beta Barrels

TMH-Benchmark

Evaluate new methods for Trans-Membrane Helix prediction

UCON

Prediction of natively unstructured regions through contact maps

Function

ECGO

Prediction of Enzymatic Activity of a Protein Sequence in Terms of Enzyme Commission (EC) Numbers

DISIS

Prediction of residues involved in DNA binding

ISIS

Prediction of residues involved in external protein-protein interactions.

LOCnet

De novo prediction of protein sub-cellular localization

LOCtree

Prediction of sub-cellular LOCalization for structural genomics targets

LOCtree2

Prediction of sub-cellular localization for all proteins in all domains of life

PiNat

Method for assessing the validity of yeast two hybrid experiments results

predictNLS

Prediction and analysis of Nuclear Localization Signals

SNAP

Evaluates the effects of single amino acid substitutions on protein function

Clustering

UniqueProt

Creating sequence-Unique Protein databases

Data-mining

NLProt

Mining Natural Language text for PROTein names and their UniProt-IDs

Databases

CellCycleDB

Database collecting and annotating proteins involved in cell-cycle control

Epitome

Database of structure-inferred antigenic epitopes.

ERGolgiDB

Archive of proteins from endoplasmic reticulum and Golgi apparatus

LocDB

LocDB is a expert curated database that collects experimental annotations for the subcellular localization of proteins in Human (Homo sapiens) and Weed (Arabidopsis thaliana)

NLSdb

Database of nuclear localization signals (NLSs) and of nuclear proteins targeted to the nucleus by NLS motifs

NMPdb

NMP-db is a database of nuclear matrix associated proteins

SNPdbe

SNPdbe is a rich database of nsSNPs augmented with effects (experimentally derived and predicted), disease associations and more

Datasets and other resources

TMHeval

Evaluation of transmembrane helix prediction methods: dataset and evalutation scores

OMIA

Predicted molecular effects tell stories about system level of disease