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Rost, Burkhard
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2020
Lai J-S
,
Rost B
,
Kobe B
,
Boden M
.
Evolutionary model of protein secondary structure capable of revealing new biological relationships.
Proteins. 2020 ;88(9):1251-1259.
Zaucha J
,
Heinzinger M
,
Kulandaisamy A
,
Kataka E
,
Salvádor ÓLlorian
,
Popov P
,
Rost B
,
M Gromiha M
,
Zhorov BS
,
Frishman D
.
Mutations in transmembrane proteins: diseases, evolutionary insights, prediction and comparison with globular proteins.
Brief Bioinform. 2020 .
Qiu J
,
Bernhofer M
,
Heinzinger M
,
Kemper S
,
Norambuena T
,
Melo F
,
Rost B
.
ProNA2020 predicts protein-DNA, protein-RNA, and protein-protein binding proteins and residues from sequence.
J Mol Biol. 2020 ;432(7):2428-2443.
Reeb J
,
Wirth T
,
Rost B
.
Variant effect predictions capture some aspects of deep mutational scanning experiments.
BMC Bioinformatics. 2020 ;21(1):107.
Dallago C
,
Goldberg T
,
Andrade-Navarro MAngel
,
Alanis-Lobato G
,
Rost B
.
Visualizing Human Protein-Protein Interactions and Subcellular Localizations on Cell Images Through CellMap.
Curr Protoc Bioinformatics. 2020 ;69(1):e97.
2019
Zhou N
,
Jiang Y
,
Bergquist TR
,
Lee AJ
,
Kacsoh BZ
,
Crocker AW
,
Lewis KA
,
Georghiou G
,
Nguyen HN
,
Hamid MNafiz
, et al.
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.
Genome Biol. 2019 ;20(1):244.
Littmann M
,
Goldberg T
,
Seitz S
,
Boden M
,
Rost B
.
Correction to: Detailed prediction of protein sub-nuclear localization.
BMC Bioinformatics. 2019 ;20(1):727.
Peeken JC
,
Bernhofer M
,
Spraker MB
,
Pfeiffer D
,
Devecka M
,
Thamer A
,
Shouman MA
,
Ott A
,
Nüsslin F
,
Mayr NA
, et al.
CT-based radiomic features predict tumor grading and have prognostic value in patients with soft tissue sarcomas treated with neoadjuvant radiation therapy.
Radiother Oncol. 2019 .
Littmann M
,
Goldberg T
,
Seitz S
,
Boden M
,
Rost B
.
Detailed prediction of protein sub-nuclear localization.
BMC Bioinformatics. 2019 ;20(1):205.
Scheibenreif L
,
Littmann M
,
Orengo C
,
Rost B
.
FunFam protein families improve residue level molecular function prediction.
BMC Bioinformatics. 2019 ;20(1):400.
Miller M
,
Vitale D
,
Kahn PC
,
Rost B
,
Bromberg Y
.
funtrp: identifying protein positions for variation driven functional tuning.
Nucleic Acids Res. 2019 ;47(21):e142.
Heinzinger M
,
Elnaggar A
,
Wang Y
,
Dallago C
,
Nechaev D
,
Matthes F
,
Rost B
.
Modeling aspects of the language of life through transfer-learning protein sequences.
BMC Bioinformatics. 2019 ;20(1):723.
2018
Peeken JC
,
Goldberg T
,
Pyka T
,
Bernhofer M
,
Wiestler B
,
Kessel KA
,
Tafti PD
,
Nüsslin F
,
Braun AE
,
Zimmer C
, et al.
Combining multimodal imaging and treatment features improves machine learning-based prognostic assessment in patients with glioblastoma multiforme.
Cancer Med. 2018 .
Marot-Lassauzaie V
,
Bernhofer M
,
Rost B
.
Correcting mistakes in predicting distributions.
Bioinformatics. 2018 .
Schafferhans A
,
O'Donoghue SI
,
Heinzinger M
,
Rost B
.
Dark Proteins Important for Cellular Function.
Proteomics. 2018 ;18(21-22):e1800227.
Schelling M
,
Hopf TA
,
Rost B
.
Evolutionary couplings and sequence variation effect predict protein binding sites.
Proteins. 2018 .
Mahlich Y
,
Steinegger M
,
Rost B
,
Bromberg Y
.
HFSP: high speed homology-driven function annotation of proteins.
Bioinformatics. 2018 ;34(13):i304-i312.
Cejuela JMiguel
,
Vinchurkar S
,
Goldberg T
,
Shankar MSollepura
,
Baghudana A
,
Bojchevski A
,
Uhlig C
,
Ofner A
,
Raharja-Liu P
,
Jensen LJuhl
, et al.
LocText: relation extraction of protein localizations to assist database curation.
BMC Bioinformatics. 2018 ;19(1):15.
Bernhofer M
,
Goldberg T
,
Wolf S
,
Ahmed M
,
Zaugg J
,
Boden M
,
Rost B
.
NLSdb-major update for database of nuclear localization signals and nuclear export signals.
Nucleic Acids Res. 2018 ;46(D1):D503-D508.
Tran L
,
Hamp T
,
Rost B
.
ProfPPIdb: Pairs of physical protein-protein interactions predicted for entire proteomes.
PLoS One. 2018 ;13(7):e0199988.
Peeken JC
,
Bernhofer M
,
Wiestler B
,
Goldberg T
,
Cremers D
,
Rost B
,
Wilkens JJ
,
Combs SE
,
Nüsslin F
.
Radiomics in radiooncology - Challenging the medical physicist.
Phys Med. 2018 ;48:27-36.
Sanghai ZAssur
,
Liu Q
,
Clarke OB
,
Belcher-Dufrisne M
,
Wiriyasermkul P
,
M Giese H
,
Leal-Pinto E
,
Kloss B
,
Tabuso S
,
Love J
, et al.
Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Elife. 2018 ;7.
Cevost J
,
Vaillant C
,
Meyer S
,
Rost B
.
ThreaDNA: predicting DNA mechanics' contribution to sequence selectivity of proteins along whole genomes.
Bioinformatics. 2018 ;34(4):609-616.
Peeken JC
,
Goldberg T
,
Knie C
,
Komboz B
,
Bernhofer M
,
Pasa F
,
Kessel KA
,
Tafti PD
,
Rost B
,
Nüsslin F
, et al.
Treatment-related features improve machine learning prediction of prognosis in soft tissue sarcoma patients.
Strahlenther Onkol. 2018 ;194(9):824-834.
2017
Dallago C
,
Goldberg T
,
Andrade-Navarro MAngel
,
Alanis-Lobato G
,
Rost B
.
CellMap visualizes protein-protein interactions and subcellular localization.
F1000Res. 2017 ;6:1824.
Mahlich Y
,
Reeb J
,
Hecht M
,
Schelling M
,
De Beer TAndries Pe
,
Bromberg Y
,
Rost B
.
Common sequence variants affect molecular function more than rare variants?
. Sci Rep. 2017 ;7(1):1608.
Hücker SM
,
Ardern Z
,
Goldberg T
,
Schafferhans A
,
Bernhofer M
,
Vestergaard G
,
Nelson CW
,
Schloter M
,
Rost B
,
Scherer S
, et al.
Discovery of numerous novel small genes in the intergenic regions of the Escherichia coli O157:H7 Sakai genome.
PLoS One. 2017 ;12(9):e0184119.
Cejuela JMiguel
,
Bojchevski A
,
Uhlig C
,
Bekmukhametov R
,
Karn SKumar
,
Mahmuti S
,
Baghudana A
,
Dubey A
,
Satagopam VP
,
Rost B
.
nala: text mining natural language mutation mentions.
Bioinformatics. 2017 .
2016
Goldberg T
,
Rost B
,
Bromberg Y
.
Computational prediction shines light on type III secretion origins.
Sci Rep. 2016 ;6:34516.
Ramilowski JA
,
Goldberg T
,
Harshbarger J
,
Kloppmann E
,
Lizio M
,
Satagopam VP
,
Itoh M
,
Kawaji H
,
Carninci P
,
Rost B
, et al.
Corrigendum: A draft network of ligand-receptor-mediated multicellular signalling in human.
Nat Commun. 2016 ;7:10706.
Jiang Y
,
Oron TRonnen
,
Clark WT
,
Bankapur AR
,
D'Andrea D
,
Lepore R
,
Funk CS
,
Kahanda I
,
Verspoor KM
,
Ben-Hur A
, et al.
An expanded evaluation of protein function prediction methods shows an improvement in accuracy.
Genome Biol. 2016 ;17(1):184.
Yachdav G
,
Wilzbach S
,
Rauscher B
,
Sheridan R
,
Sillitoe I
,
Procter J
,
Lewis SE
,
Rost B
,
Goldberg T
.
MSAViewer: interactive JavaScript visualization of multiple sequence alignments.
Bioinformatics. 2016 .
Reeb J
,
Hecht M
,
Mahlich Y
,
Bromberg Y
,
Rost B
.
Predicted Molecular Effects of Sequence Variants Link to System Level of Disease.
PLoS Comput Biol. 2016 ;12(8):e1005047.
Rost B
,
Radivojac P
,
Bromberg Y
.
Protein function in precision medicine: deep understanding with machine learning.
FEBS Lett. 2016 .
Ardiccioni C
,
Clarke OB
,
Tomasek D
,
Issa HA
,
von Alpen DC
,
Pond HL
,
Banerjee S
,
Rajashankar KR
,
Liu Q
,
Guan Z
, et al.
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
Nat Commun. 2016 ;7:10175.
Petrou VI
,
Herrera CM
,
Schultz KM
,
Clarke OB
,
Vendome J
,
Tomasek D
,
Banerjee S
,
Rajashankar KR
,
Dufrisne MBelcher
,
Kloss B
, et al.
Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation.
Science. 2016 ;351(6273):608-12.
Bernhofer M
,
Kloppmann E
,
Reeb J
,
Rost B
.
TMSEG: Novel prediction of transmembrane helices.
Proteins. 2016 .
Neuhaus K
,
Landstorfer R
,
Fellner L
,
Simon S
,
Schafferhans A
,
Goldberg T
,
Marx H
,
Ozoline ON
,
Rost B
,
Kuster B
, et al.
Translatomics combined with transcriptomics and proteomics reveals novel functional, recently evolved orphan genes in Escherichia coli O157:H7 (EHEC).
BMC Genomics. 2016 ;17(1):133.
2015
Yachdav G
,
Goldberg T
,
Wilzbach S
,
Dao D
,
Shih I
,
Choudhary S
,
Crouch S
,
Franz M
,
García A
,
García LJ
, et al.
Anatomy of BioJS, an open source community for the life sciences.
Elife. 2015 ;4.
O'Donoghue SI
,
Sabir KS
,
Kalemanov M
,
Stolte C
,
Wellmann B
,
Ho V
,
Roos M
,
Perdigão N
,
Buske FA
,
Heinrich J
, et al.
Aquaria: simplifying discovery and insight from protein structures.
Nat Methods. 2015 ;12(2):98-9.
Hecht M
,
Bromberg Y
,
Rost B
.
Better prediction of functional effects for sequence variants.
BMC Genomics. 2015 ;16 Suppl 8:S1.
Ramilowski JA
,
Goldberg T
,
Harshbarger J
,
Kloppman E
,
Lizio M
,
Satagopam VP
,
Itoh M
,
Kawaji H
,
Carninci P
,
Rost B
, et al.
A draft network of ligand-receptor-mediated multicellular signalling in human.
Nat Commun. 2015 ;6:7866.
Vicedo E
,
Schlessinger A
,
Rost B
.
Environmental Pressure May Change the Composition Protein Disorder in Prokaryotes.
PLoS One. 2015 ;10(8):e0133990.
Reeb J
,
Kloppmann E
,
Bernhofer M
,
Rost B
.
Evaluation of transmembrane helix predictions in 2014.
Proteins. 2015 ;83(3):473-84.
Hamp T
,
Rost B
.
Evolutionary profiles improve protein-protein interaction prediction from sequence.
Bioinformatics. 2015 .
Karp PD
,
Berger B
,
Kovats D
,
Lengauer T
,
Linial M
,
Sabeti P
,
Hide W
,
Rost B
.
ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.
F1000Res. 2015 ;4:12.
Karp PD
,
Berger B
,
Kovats D
,
Lengauer T
,
Linial M
,
Sabeti P
,
Hide W
,
Rost B
.
Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus.
Bioinformatics. 2015 ;31(4):616-7.
Hamp T
,
Rost B
.
More challenges for machine-learning protein interactions.
Bioinformatics. 2015 .
Vicedo E
,
Gasik Z
,
Dong Y-A
,
Goldberg T
,
Rost B
.
Protein disorder reduced in Saccharomyces cerevisiae to survive heat shock.
F1000Res. 2015 ;4:1222.
Guo Y
,
Kalathur RC
,
Liu Q
,
Kloss B
,
Bruni R
,
Ginter C
,
Kloppmann E
,
Rost B
,
Hendrickson WA
.
Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science. 2015 ;347(6221):551-5.
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