ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.

TitleISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.
Publication TypeJournal Article
Year of Publication2015
AuthorsKarp, PD, Berger, B, Kovats, D, Lengauer, T, Linial, M, Sabeti, P, Hide, W, Rost, B
JournalF1000Res
Volume4
Pagination12
Date Published2015
ISSN2046-1402
Abstract

Speed is of the essence in combating Ebola; thus, computational approaches should form a significant component of Ebola research. As for the development of any modern drug, computational biology is uniquely positioned to contribute through comparative analysis of the genome sequences of Ebola strains as well as 3-D protein modeling. Other computational approaches to Ebola may include large-scale docking studies of Ebola proteins with human proteins and with small-molecule libraries, computational modeling of the spread of the virus, computational mining of the Ebola literature, and creation of a curated Ebola database. Taken together, such computational efforts could significantly accelerate traditional scientific approaches. In recognition of the need for important and immediate solutions from the field of computational biology against Ebola, the International Society for Computational Biology (ISCB) announces a prize for an important computational advance in fighting the Ebola virus. ISCB will confer the ISCB Fight against Ebola Award, along with a prize of US$2,000, at its July 2016 annual meeting (ISCB Intelligent Systems for Molecular Biology (ISMB) 2016, Orlando, Florida).

DOI10.12688/f1000research.6038.1
Alternate JournalF1000Res
PubMed ID26097686
PubMed Central IDPMC4457108