Lecture 'Protein Prediction II'

Type:

Lecture (4 SWS) + Exercise (2 SWS)

Ects:

8.0

Lecturer

Burkhard Rost  (lecture)
Tobias Hamp, Christian Schäfer, Esmeralda Vicedo (exercise)

Rotation:

Wednesday 12:00-13:30 (lecture)
Friday, 10:30-12:00 (lecture)
Friday, change (!): 13:30-15:00 (exercise)

Place:

Lecture: (Multimedia room) MI 00.13.009A
Exercise: (Seminar room 'John von Neumann') MI 00.11.038

Language:

English

 

Announcements:

Note (!) starting Nov 12 friday's lecture will be held in room 00.08.038 

The videos can now be downloaded on this page

No Lecture: Dec 22

Last Lecture: Feb 2

Examen: Feb 9,12:00 (MI 00.13.009A, Multimedia room)

  • Makeup: May 6

Content

This lecture continues the 'Protein Prediction' lecture. Topics will include (but not be limited to):

  • Predicting protein function using sequence: sequence alignments, multiple sequence alignments, motifs, domain assignment, annotation transfer by homology, ab initio predictions.
  • Predicting protein function using structure: structural alignments, structural motifs, annotation transfer via structure similarity.
  • From structure prediction to function prediction: comparative modeling; prediction of: secondary structure, hydrophilicity profiles, solvent accessibility, transmembrane segments, disordered regions, contact maps, functional residues; template free modeling.
  • Machine learning.

Materials Lecture

pp2_201010120_our-work.pdf

Lecture 1 (10-20-2010)

13.0 M

pp2_20101103_intro_func1.pdf

Lecture 4 (11-03-2010)

12.0 M

pp2_20101112_intro_func2.pdf

Lecture 6 (11-12-2010)

5.0 M

pp2_20101117_intro_func3.pdf

Lecture 7 (11-17-2010)

3.1 M

pp2_20101203_localization1.pdf

Lecture 10 (12-03-2010)

5.8 M

pp2_20101208_localization2.pdf

Lecture 11 (12-08-2010)

4.1 M

pp2_20110128_snap.pdf

Lecture 16 (01-28-2011)

6.9 M

Videos Lecture

pp2_20101020.mp4

Lecture 1 (10-20-2010)

329 M

pp2_20101027.mp4

Lecture 2 (10-27-2010)

289 M

pp2_20101029.mp4

Lecture 3 (10-29-2010)

258 M

pp2_20101103.mp4

Lecture 4 (11-03-2010)

151 M

pp2_20101110.mov

Lecture 5 (11-10-2010) - Jenny Gu

214 M

pp2_20101112.avi

Lecture 6 (11-12-2010)

323 M

pp2_20101117.mov

Lecture 7 (11-17-2010)

256 M

pp2_20101126.mp4

Lecture 8 (11-26-2010)

265 M

pp2_20101201.avi

Lecture 9 (12-01-2010)

316 M

pp2_20101203.avi

Lecture 10 (12-03-2010)

256 M

pp2_20101208.wmv

Lecture 11 (12-08-2010)

258 M

pp2_20101215.wmv

Lecture 12 (12-15-2010) - Prof. Dr. Christopher Baker

302 M

pp2_20110119.wmv

Lecture 13 (01-19-2011) - Dr. Marco De Vivo (part 1/2)

523 M

pp2_20110121.mp4

Lecture 14 (01-21-2011) - Dr. Marco De Vivo (part 2/2)

337 M

pp2_20110126.mp4

Lecture 15 (01-26-2011)

400 M

pp2_20110128.mp4

Lecture 16 (01-28-2011)

437 M

Materials Exercise

exercise1.pdf

Sheet 1

72 K

exercise2.pdf

Sheet 2

74 K

exercise3_V4.pdf

Sheet 3 Version 4

116 K

exercise4_V2.pdf

Sheet 4 Version 2

102 K