NO AUTO-SUBMISSION ALLOWED! THE SNAP SERVICE IS AVAIALBLE FOR MANUAL SUBMISSION OF INDIVIDUAL JOBS.
FOR EXTENSIVE USE OF THE SNAP SOFTWARE WE STRONGLY RECOMMEND YOU INSTALL THE PACKAGE LOCALLY OR CONTACT US TO DISCUSS YOUR NEEDS.

E-mail adress help Result sent by e-mail, please provide your e-mail address



Input sequence
Entry name
Paste, or type in your sequence
  • amino acids in one-letter code
  • any number of white spaces allowed
  • non-standard amino acids to 'U'
  • sequence only (NO ">" or sequence name)


Input substitutions pattern (OPTIONAL) help Substitution pattern format for in silico mutagenesis

Total mutants:

0
Please note, Internet Explorer may have problems generating mutant lists. We are aware of the problem and ask that you bear with us as we are trying to fix it!
  • XposY where X is the wild type amino acid, Y is the mutant, and pos is the number of the residue (pos=1 for N-term)
  • X is NOT required and a star (* = all possible) can replace either pos or Y
  • Press Generate Mutants to see all possible mutations in the text field below
  • Mutations may be added/removed before hitting Submit, but no more than 150 may be submitted per run


Input substitutions help Substitutions format for a list of mutants
  • Paste or type in your substitutions in format XposY, where X and Y are any amino acids and "pos" is the position in sequence (e.g A365N)
  • separate multiple subsitutions by ","
  • any number of white spaces is allowed
  • no more than 150 mutants may be submitted per run


Advanced options
Min reliability index:
help integer between 0 and 9
Min expected accuracy: %
help number between 50 and 100


Copyright © 2010 Yana Bromberg and Brukhard Rost, ROSTLAB all rights reserved. | The use of this service is free for academia all others should inquire about a commercial license by writing to biosof llc