CUBIC: Columbia University Bioinformatics Center PredictProtein : sequence analysis, prediction of protein function and structure META-PP - EVA - NLProt - UniqueProt - NORSp - CHOP - PredictNLS - LOCtree - PROFtmb - TMH-Benchmark - DSSPcont - selected WWW links   daily highlight: CHOP (CHOPping proteins into domain-like fragments) PEP :Predictions for Entire Proteomes NLSdb - LOCtarget - LOCkey - LOC3d - LOChom - NMPdb - ER-GolgiDB - CellCycleDB -   daily highlight: LOC3D (Predicted subcellular LOCalization for euk. PDB chains) We currently have people in our lab, working on prediction methods for AA-chain- interactions, domain-borders, PDB B-factors, protein-function (enzyme classes), subcellular and subnuclear localization, transmembrane beta-barrels/alpha-helical proteins and SNPs' functional effects on proteins. We also recently started developing a data-mining technique to assign UniProt IDs to protein names in natural language text. (read more) About the CUBIC: Our main goal is to predict protein structure and protein function using sequence information, evolutionary information and results from other predictions. We work with neural networks, support-vector machines, Tree-algorithms and Bayesian classifiers. (read more) CUBIC   Columbia University Department of Biochemistry & Molecular Biophysics 1130 St. Nicholas Ave, 8th. floor, Room 805 New York, N.Y. 10032 USA Email assistant@rostlab.org Tel +1-212-851 4669 / Fax +1-212-851 5149