Evolution teaches prediction
Is Bioinformatics up to the data deluge?
Sequence comparison: do we know what we do?
- conservation of structure and function
Structure prediction: where are we today?
How to learn from the evolutionary odyssey?
- secondary structure
- transmembrane proteins
- solvent accessibility
Are 1D predictions useful?
- sub-cellular localisation
- whole genomes
- 3D structure: threading
- floppy regions